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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinopathy of prematurity (ROP)
ncRNA name VEGF164 shRNA
ncRNA Category shRNA
Disease name retinopathy of prematurity (ROP)
Species Rattus norvegicus
Tissues/Cell_line rat Müller cell line rMC-1; retinas
Methods shRNA knockdown, fluorescence microscope, immunofluorescence staining, ELISA
Expression pattern associated
Functional description Short hairpin RNA to Müller cell VEGF164 maintained long-term inhibition of IVNV and limited cell death compared with shRNA to VEGFA.
PubMed ID 24425851
Year 2014
Title Targeting Müller cell-derived VEGF164 to reduce intravitreal neovascularization in the rat model of retinopathy of prematurity.
Drug-related ncRNA NA

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